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As of September 2023 it is on the FDA's Category 2 list of bulk drug substances that may not be compounded due to significant safety risks, and the agency has scheduled a Pharmacy Compounding Advisory Committee (PCAC) review for July 2026 covering proposed uses in opioid withdrawal, chronic insomnia, and narcolepsy

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is supported by NIH research grant OT2OD032581 and a research grant from the American College of Clinical Pharmacy, reports consulting fees from Bayer AG, Sanofi, Boehringer Ingelheim, Eli Lilly and Proteomics International, reports payments for lectures from Dexcom and Med Learning Group and serves on the Board of Directors for the American Diabetes Association